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Diabetic retinopathy affects blood vessels in the light-sensitive tissue called the retina that lines the back of the eye. Glaucoma. Standards of Medical Care in Diabetes Р2015. However, patients need to be aware if any medication they are taking will affect the eyes. About Diabetic Eye Disease Diabetic eye disease comprises a group of eye conditions that affect people with diabetes. New blood vessels may grow in the front part of your eye and interfere with the normal flow of fluid out of the eye, causing pressure in the eye to build up glaucoma. acct study participants who kept their blood glucose level as close to normal as possible were significantly less likely than those without optimal glucose control to develop diabetic retinopathy, as well as kidney and nerve diseases. Almost all people with diabetes show signs of retinal damage after about 20 years of living with the condition.

3, 2017) – A more powerful version of an anti-inflammatory molecule already circulating in our blood may help protect our vision in the face of diabetes. Diabetic retinopathy resulting from high circulating levels of glucose is the leading cause of blindness in adults. Now scientists have evidence that a man-made version of soluble gp130, or sgp130, that is 10 times more powerful than the natural one, may help avoid high levels of inflammation in the eye that occur in diabetes and avert the retinal destruction that typically follows. “What we are trying to do is inhibit this pathway so there will be no more signaling,” said Dr. Shruti Sharma, vascular and endothelial biologist in the Center for Biotechnology and Genomic Medicine at the Medical College of Georgia at Augusta University. is talking about the pro-inflammatory cascade that can result when high levels of glucose in the blood prompt high circulating levels of the immune-system driver IL-6. High circulating IL-6 has been found in the blood as well as the fluid portion of the eyes of patients with diabetic retinopathy. When circulating levels of IL-6 increase, so do levels of its receptor, IL-6R, which is required for IL-6 to be active. These floating inflammation drivers enable something called trans-signaling – where receptors aren’t directly found on the affected cells themselves – and there is emerging evidence from Sharma’s lab and others that it’s a major player in inflammation-driven diseases like diabetic retinopathy, inflammatory bowel disease, even atherosclerosis. In this case, the body appears to have a check system: Sgp130 also is traveling in the bloodstream where it can essentially trap the IL-6/IL-6 receptor complex and keep it from crossing cell membranes to promote inflammation. However, in the altered face of diabetes, apparently its action is not always sufficient.

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The contrast agent can then be seen coursing through the blood vessels in your retina. Who is at risk for diabetic¬†retinopathy? In more advanced stages, the retina can become detached, causing blindness. A person with retinopathy could have it for years with no pain or other symptoms until the condition progresses enough to cause vision loss. The macula doesn’t function properly when it is swollen. Leitgeb A, et al. Mayo Clinic, Rochester, Finn. It is used to keep vessels from leaking, or to shrink abnormal vessels. Vision is gradually lost because the retina and nerve are damaged. In scatter photo coagulation also called pan retinal photo coagulation, the eye care professional makes hundreds of burns in a polka-dot pattern on two or more occasions. Recommended Related to Diabetes makes heart disease more likely. As with diabetic retinopathy, there may be no symptoms early in hypertensive retinopathy.

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